The Indian Massacre of 1622 was an attack on the settlements of the Virginia Colony by the tribes of the Powhatan Confederacy under their leader Opchanacanough (l. 1554-1646) and his brother Opitchapam (d. c. 1630) resulting in the deaths of 347 colonists. Credit for its success is always given to Opchanacanough with Opitchapam playing a secondary role.
This is a companion discussion topic for the original content at https://www.worldhistory.org/Indian_Massacre_of_1622/.